Transplacental carcinogenesis by stilbestrol

摘要: Herbst, Ulfelder and Poskanzer1 were the first to notice a high correlation between adenocarcinoma of vagina in adolescent girls prior maternal ingestion diethylstilbestrol. This is stunning observation. It supported by five more cases described this issue Greenwald et al. In previous editorial2 Langmuir discussed some clinical scientific implications discovery. Further speculations are now warranted. Neither Herbst nor studied large number mothers with repeated bleeding or pregnancy loss who did not receive stilbestrol. omission irrelevant, however, because extreme rarity . . .