作者: Theodora H Darlenska , Daniel Pella , Jan Fedacko , Krasimira Hristova , Branislav Milovanovic
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摘要: Chrono-cardiology is the science which refers to cardiovascular function and dysfunction according time structure. Guidelines from various agencies for management of diseases (CVDs) emphasize that necessity, choice intensity treatment should be determined by individual’s probability an event (risk) within a given period predisposes CVD deaths. There little consideration chronotherapy based on data collected, example, during 24 hours, can fail detect vascular variability disorders not yet popularly known among cardiologists. A knowledge chronocardiology may useful in reducing dose agent as well its adverse effects while providing several fold greater benefit, thereby optimising therapeutic efficacy toxicity.