摘要: In contrast to many of the malignant tumors that occur in central nervous system adults, management, responses therapy, and future perspectives children with lesions brain hold considerable promise. Within past 5 years, remarkable progress has been made our understanding basic biology molecular genetics several pediatric including medulloblastoma, ependymoma, atypical teratoid rhabdoid tumour, high grade glioma/diffuse intrinsic pontine glioma. The recent literature neuro-oncology was reviewed, a summary major findings are presented. Meaningful sub-classifications these have arisen, placing into discrete categories disease requirements for targeted therapy. While mainstay therapy 30 years combination irradiation conventional chemotherapy, now advent resolution genetic mapping, therapies emerged, less emphasis is being placed on craniospinal irradiation. this article, present perspective malignancy reviewed detail. offers significant hope patients tumours.
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