특집 : 진행성 노인 대장암에 대한 항암요법

摘要: Colorectal cancer (CRC) affects largely elderly populations. However, older patients with CRC are generally excluded from randomized clinical trials, and the healthy subjects who recruited not representative of general patient population. Nevertheless, recent data trials specifically targeting related subgroup analyses indicate that well-selected can have a similar response to younger patients. Chronological age should determine candidacy for adjuvant or palliative chemotherapy in CRC. The appropriate management would mean they could receive aggressive regimen patients, whereas care frail those short life expectancy focus on palliation. use comprehensive geriatric assessment allow safe beneficial regimens (Korean J Med 2014;87:530-536)