Drugs for the Prevention and Treatment of Bronchopulmonary Dysplasia.
作者： Erica W. Mandell , Panagiotis Kratimenos , Steven H. Abman , Robin H. Steinhorn
DOI: 10.1016/J.CLP.2019.02.011
关键词:
摘要: Rates of bronchopulmonary dysplasia (BPD) are increasing. After preterm birth, there important developmental periods in which neonates more vulnerable to stressful events. These opportunities for pharmacologic interventions. Many drugs remain inadequately tested and no new have been approved than 25 years BPD prevention or therapy. More progress is needed defining appropriate end points based on the pathophysiology postdischarge chronic pulmonary insufficiency prematurity develop effective drugs. In addition, much work better define perinatal factors, early postnatal findings, physiologic phenotypes endotypes.
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