The transplacental transfer of IgG subclasses: influence of prematurity and low birthweight in the Gambian population.
作者： B. J. Okoko , H. L. Wesumperuma , J. Fern , L. K. Yamuah , C. A. Hart
DOI: 10.1179/027249302125001985
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摘要: Abstract Having established previously that prematurity in The Gambia is associated with impaired maternofetal transfer of some specific antibodies, we investigated the influence low birthweight and on placental IgG subclasses 180 Gambian mothers their newborn babies. A physician-blinded, cross-sectional study mother-baby pairs was carried out labour ward Bansang Hospital, Gambia. Paired maternal cord serum samples were collected from newborns. Serum subclass levels measured by laser nephelometry. Placental all significantly reduced preterm newborns compared term (p<0.01). In (LBW) babies, IgG1 (p=0.03) IgG2 (p<0.01) subclasses, but not IgG3 IgG4, reduced. neonates an adequate a birthweight, transferred efficiency, an...
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