Effect of massive dose vitamin A on morbidity and mortality in Indian children.

作者: K. Vijayaraghavan , G. Radhaiah , B.Surya Prakasam , KV.R. Sarma , V. Reddy

DOI: 10.1016/0140-6736(90)92895-O

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摘要: The effect of vitamin A supplementation on preschool child morbidity and mortality was assessed in a prospective double-blind placebo-controlled study around Hyderabad, India. Every six months 200,000 IU given to 7691 children (treatment group) whereas 8084 received placebo (control group). Morbidity data were collected every three months. Risk respiratory infection higher with mild xerophthalmia than normal eyes. Vitamin had no status. Mortality rates similar the two groups; it highest who did not receive either or placebo. findings suggest that alone may reduce mortality.

参考文章(10)
A N Naidu, R C Milton, V Reddy, Mild vitamin A deficiency and childhood morbidity--an Indian experience. The American Journal of Clinical Nutrition. ,vol. 46, pp. 827- 829 ,(1987) , 10.1093/AJCN/46.5.827
A Sommer, J Katz, I Tarwotjo, Increased risk of respiratory disease and diarrhea in children with preexisting mild vitamin A deficiency. The American Journal of Clinical Nutrition. ,vol. 40, pp. 1090- 1095 ,(1984) , 10.1093/AJCN/40.5.1090
Alfred Sommer, Gusti Hussaini, Ignatius Tarwotjo, Djoko Susanto, INCREASED MORTALITY IN CHILDREN WITH MILD VITAMIN A DEFICIENCY The Lancet. ,vol. 322, pp. 585- 588 ,(1983) , 10.1016/S0140-6736(83)90677-3
MASUMA MAMDANI, DAVID ROSS, Vitamin A supplementation and child survival: magic bullet or false hope? Health Policy and Planning. ,vol. 4, pp. 273- 294 ,(1989) , 10.1093/HEAPOL/4.4.273
Alfred Sommer, Gusti Hussaini, Ignatius Tarwotjo, Djoko Susanto, Tito Soegiharto, INCIDENCE, PREVALENCE, AND SCALE OF BLINDING MALNUTRITION The Lancet. ,vol. 317, pp. 1407- 1408 ,(1981) , 10.1016/S0140-6736(81)92581-2
D. L. Wilhelm, Regeneration of the tracheal epithelium in the vitamin-A-deficient rat The Journal of Pathology and Bacteriology. ,vol. 67, pp. 361- 365 ,(1954) , 10.1002/PATH.1700670209
K Menon, K Vijayaraghavan, Sequelae of severe xerophthalmia—a follow-up study The American Journal of Clinical Nutrition. ,vol. 33, pp. 218- 220 ,(1980) , 10.1093/AJCN/33.2.218
Alfred Sommer, Edi Djunaedi, A.A Loeden, Ignatius Tarwotjo, KeithP West, Robert Tilden, Lisa Mele, The Aceh Study Group, Impact of vitamin A supplementation on childhood mortality. A randomised controlled community trial. The Lancet. ,vol. 327, pp. 1169- 1173 ,(1986) , 10.1016/S0140-6736(86)91157-8
I Tarwotjo, A Sommer, K P West, E Djunaedi, L Mele, B Hawkins, Influence of participation on mortality in a randomized trial of vitamin A prophylaxis. The American Journal of Clinical Nutrition. ,vol. 45, pp. 1466- 1471 ,(1987) , 10.1093/AJCN/45.6.1466
Rao Tv, Rao Dh, Swaminathan Mc, Vijayaraghavan K, Assessment of nutritional status by Village Health Guides. Indian Pediatrics. ,vol. 22, pp. 669- ,(1985)