The effect of timing of clot removal on chronic vasospasm in a primate model

摘要: ✓ The effect of complete clot removal at times from 48 to 96 hours after subarachnoid hemorrhage (SAH) on the development chronic cerebral vasospasm was evaluated determine whether there is a critical point which ineffective in preventing vasospasm. Thirty cynomolgus monkeys were randomized one five groups: sham-operated group, SAH (48-hour group), 72 (72-hour (96-hour and placement only (clot group). Standard microsurgical techniques used dissect bilaterally major arteries free arachnoid. An autologous blood averaging 4.2 gm placed around vessels space 48-hour, 72-hour, 96-hour, groups. Physiological saline instilled into animals. Animals clot-removal groups underwent surgical determined ...