Sex Assignment in Disorders of Sex Development

摘要: Disorders of sex development (DSD) are relatively rare conditions with diverse pathophysiology, which usually present in the newborn or adolescent periods. These very heterogeneous and can a variety different ways, most commonly ambiguous genitalia noticed period delayed puberty adolescents. The impact these disorders on lives patients their families should not be underestimated. clinical situations often difficult to manage, particularly those cases where rearing is uncertain. needs each individual patient presenting DSD must fully considered, along appropriate, cultural practices. multidisciplinary team involved from early diagnosis ethical principles considered at all stages management condition. Key Concepts: Disorders periods. There three broad groups DSD: chromosome DSD; 46,XY 46,XX DSD. Where there uncertainty about patient, assignment until appropriate investigations have been carried out. A an stage. The psychosocial implications for family patient. Keywords: ambiguous genitalia; gender; multidisciplinary team; sex development; ethics