Conservative Treatment in Diverticulitis Patients with Pericolic Extraluminal Air and the Role of Antibiotic Treatment

作者: H. E. Bolkenstein , S. T. van Dijk , E. C. J. Consten , B. G. F. Heggelman , C. M. A. Hoeks

DOI: 10.1007/S11605-019-04153-9

关键词:

摘要: Recently published studies advocate a conservative approach with observation and antibiotic treatment in diverticulitis patients pericolic air on computed tomography (CT). The primary aim of this study was to assess the clinical course initially conservatively treated isolated identify risk factors for failure. secondary outcome non-antibiotic treatment. Patient data from retrospective cohort complicated were combined DIABOLO trial, randomised controlled trial comparing uncomplicated diverticulitis. present identified all Hinchey 1A CT. Pericolic defined as located < 5 cm affected segment colon. failure management which need percutaneous abscess drainage or emergency surgery within 30 days after presentation. A multivariable logistic regression clinical, radiological laboratorial parameters respect performed. total 109 included study. Fifty-two (48%) antibiotics. Nine (8%) failed management, seven (13%) group two (4%) (p = 0.083). Only (increased) CRP level at presentation an independent predictor Conservative is suitable strategy. Moreover, might be reasonable selected patients.

参考文章(28)
A. Tursi, A. Papa, S. Danese, Review article: the pathophysiology and medical management of diverticulosis and diverticular disease of the colon Alimentary Pharmacology & Therapeutics. ,vol. 42, pp. 664- 684 ,(2015) , 10.1111/APT.13322
Massimo Sartelli, Frederick A Moore, Luca Ansaloni, Salomone Di Saverio, Federico Coccolini, Ewen A Griffiths, Raul Coimbra, Ferdinando Agresta, Boris Sakakushev, Carlos A Ordoñez, Fikri M Abu-Zidan, Aleksandar Karamarkovic, Goran Augustin, David Costa Navarro, Jan Ulrych, Zaza Demetrashvili, Renato B Melo, Sanjay Marwah, Sanoop K Zachariah, Imtiaz Wani, Vishal G Shelat, Jae Il Kim, Michael McFarlane, Tadaja Pintar, Miran Rems, Miklosh Bala, Offir Ben-Ishay, Carlos Augusto Gomes, Mario Paulo Faro, Gerson Alves Pereira, Marco Catani, Gianluca Baiocchi, Roberto Bini, Gabriele Anania, Ionut Negoi, Zurabs Kecbaja, Abdelkarim H Omari, Yunfeng Cui, Jakub Kenig, Norio Sato, Andras Vereczkei, Matej Skrovina, Koray Das, Giovanni Bellanova, Isidoro Di Carlo, Helmut A Segovia Lohse, Victor Kong, Kenneth Y Kok, Damien Massalou, Dmitry Smirnov, Mahir Gachabayov, Georgios Gkiokas, Athanasios Marinis, Charalampos Spyropoulos, Ioannis Nikolopoulos, Konstantinos Bouliaris, Jaan Tepp, Varut Lohsiriwat, Elif Çolak, Arda Isik, Daniel Rios-Cruz, Rodolfo Soto, Ashraf Abbas, Cristian Tranà, Emanuele Caproli, Darija Soldatenkova, Francesco Corcione, Diego Piazza, Fausto Catena, A proposal for a CT driven classification of left colon acute diverticulitis World Journal of Emergency Surgery. ,vol. 10, pp. 3- 3 ,(2015) , 10.1186/1749-7922-10-3
D. Isacson, A. Thorisson, K. Andreasson, M. Nikberg, K. Smedh, A. Chabok, Outpatient, non-antibiotic management in acute uncomplicated diverticulitis: a prospective study. International Journal of Colorectal Disease. ,vol. 30, pp. 1229- 1234 ,(2015) , 10.1007/S00384-015-2258-Y
Renato Costi, François Cauchy, Alban Le Bian, Jean-François Honart, Nicolas Creuze, Claude Smadja, Challenging a classic myth: pneumoperitoneum associated with acute diverticulitis is not an indication for open or laparoscopic emergency surgery in hemodynamically stable patients. A 10-year experience with a nonoperative treatment Surgical Endoscopy and Other Interventional Techniques. ,vol. 26, pp. 2061- 2071 ,(2012) , 10.1007/S00464-012-2157-Z
Ville J. Sallinen, Ari K. Leppäniemi, Panu J. Mentula, Staging of acute diverticulitis based on clinical, radiologic, and physiologic parameters Journal of Trauma-injury Infection and Critical Care. ,vol. 78, pp. 543- 551 ,(2015) , 10.1097/TA.0000000000000540
Jörg-Peter Ritz, Kai S. Lehmann, Christoph Loddenkemper, Bernd Frericks, Heinz J. Buhr, Christoph Holmer, Preoperative CT staging in sigmoid diverticulitis—does it correlate with intraoperative and histological findings? Langenbeck's Archives of Surgery. ,vol. 395, pp. 1009- 1015 ,(2010) , 10.1007/S00423-010-0609-2
David A. Etzioni, Vicki Y. Chiu, Rebecca R. Cannom, Raoul J. Burchette, Philip I. Haigh, Maher A. Abbas, Outpatient treatment of acute diverticulitis: rates and predictors of failure. Diseases of The Colon & Rectum. ,vol. 53, pp. 861- 865 ,(2010) , 10.1007/DCR.0B013E3181CDB243
Bastiaan R. Klarenbeek, Niels de Korte, Donald L. van der Peet, Miguel A. Cuesta, Review of current classifications for diverticular disease and a translation into clinical practice. International Journal of Colorectal Disease. ,vol. 27, pp. 207- 214 ,(2012) , 10.1007/S00384-011-1314-5
Kamyar Shahedi, Garth Fuller, Roger Bolus, Erica Cohen, Michelle Vu, Rena Shah, Nikhil Agarwal, Marc Kaneshiro, Mary Atia, Victoria Sheen, Nicole Kurzbard, Martijn GH van Oijen, Linnette Yen, Paul Hodgkins, M Haim Erder, Brennan Spiegel, None, Long-term risk of acute diverticulitis among patients with incidental diverticulosis found during colonoscopy. Clinical Gastroenterology and Hepatology. ,vol. 11, pp. 1609- 1613 ,(2013) , 10.1016/J.CGH.2013.06.020
Çağdaş Ünlü, Patrick M. Gunadi, Michael F. Gerhards, Marja A. Boermeester, Bart C. Vrouenraets, Outpatient treatment for acute uncomplicated diverticulitis European Journal of Gastroenterology & Hepatology. ,vol. 25, pp. 1038- 1043 ,(2013) , 10.1097/MEG.0B013E328361DD5B