A model for enhancing evidence-based capacity to make informed policy decisions on the introduction of new vaccines in the Americas: PAHO's ProVac initiative.

摘要: New and underutilized vaccines are becoming available to combat important public health challenges. Each year, rotavirus is estimated cause approximately 111 million episodes of gastroenteritis, which requires home care, 25 clinic visits, 2 hospitalizations, 440,000 deaths in children younger than 5 years age worldwide. Children the poorest countries account for 82% deaths. An 16,000 by rotavirus-induced diarEditor’s note: The thoughtful article Dr. Andrus his colleagues describing utility Pan American Health Organization’s (PAHO’s) ProVac model1 reminds us startling childhood adult disease statistics. Whether it gastroenteritis annual or 32,000 from papillomavirus—with more 80% poor developing countries—these numbers staggering. Examples such as experience Mexico that was described Santos et al.2 show model can work very well. authors suggest three essential factors need be addressed if agencies governments attain a sustainable impact: decisions should nationally based; evidence used support must broad-based; infrastructure place based process. program objectives rather aggressive, with just five-year horizon achieve series ambitious goals. At same time, PAHO honest: organization recognizes has little choice but move this direction. serve rest world. Lessons learned will many others well they attempt similar, not aggressive approach.