Seroconversion for Lyme borreliosis Among Dutch Military

作者: Koen Vos , Alje P. Van Dam , Herman Kuiper , Hans Bruins , Lodewijk Spanjaard

DOI: 10.3109/00365549409008616

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摘要: Few prospective studies for Lyme borreliosis (LB) have been conducted among subjects at risk to acquire this disease during their work when wearing well-defined protective clothing against tick-bites. We prospectively compared the rate of seroconversion and occurrence clinical manifestations LB 2 groups Dutch military. The risk-group worked predominantly outdoors, control-group indoor activities. During outdoor work, wore long sleeves, trousers, closed around ankles high boots. Initial serum samples from 2158 military were collected immediately after entering service. From 932 (at risk-group: 469, control-group: 463) a second sample was drawn 9 12 months later. Sera tested IgG IgM antibodies by ELISA. Four persons (0.9%) in 10 (2.2%) seroconverted and/or B. burgdorferi. This difference not statistically signi...

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