Modelling and optimization of critical parameters by hybrid RSM-GA for the separation of BSA using a tubular configured MFI-type zeolite microfiltration membrane

摘要: This paper deals with the fabrication of a MFI-type zeolite membrane via an in situ hydrothermal synthesis technique on low cost porous tubular ceramic substrate. To formulate layer substrate, solution was prepared using silicate solutions. The MFI (as synthesized and calcined) characterized by X-ray diffraction (XRD), thermogravimetry (TG) Fourier transform infrared spectroscopy (FTIR) analysis. fabricated substrate as well field emission scanning electron microscopy (FESEM), porosity water permeability measurements. porosity, mean pore size were evaluated to be 51%, 0.272 μm 4.43 × 10−7 m3 m−2 s−1 kPa−1, respectively. separation efficiency terms permeate flux rejection studied BSA model protein. Three operating parameters, concentration (100–500 ppm), pH (2–4) applied pressure (68.94–275.79 kPa), optimized for better response surface methodology (RSM) followed bi-objective genetic algorithm (GA). non-linear models predicted RSM further GA. appropriate optimum conditions obtained 100 ppm, 2 275.79 kPa. These experimentally validated higher 4.63 10−5 m 81.98%, Further, compared other membranes used stated literature.