Adrenal pheochromocytoma with surrounding brown fat stimulation.

摘要: AJR:192, January 2009 chromocytomas induce hypertension through the production of catecholamines, primarily epinephrine, and, less commonly, norepinephrine. Pheochromocytomas are typically sporadic and solitary neoplasms [1]. Only a small percentage patients with have pheochromocytoma, but in those who do, complete resection functional tumor provides cure. Cross-sectional imaging such as CT or MRI is an excellent study for showing adrenal masses. Brown fat normally present fetuses infants diminishes adults to account only 1% total body mass. may metabolic thermoregulatory function. Remnants brown adult usually found neck, mediastinum, axilla, retroperitoneum, abdominal wall [2]. adipose tissue has much more sympathetic noradrenergic innervation than white [3]. Norepinephrine also regulatory function fat. Catecholamine stimulation increases number cells, stimulates lipolysis glucose transport, uncouples protein-1 expression resulting heat frequently incidental finding on FDG PET that result falsepositive findings [4]. Careful correlation coregistered images should be performed exclude any masses areas uptake. After injection radiotracer, wait imaged, controlled room temperature important prevent thermogenesis increased stimulation. In adrenergic due excess catecholamine production, abundant normal adults. The localization these likely results from transport related norepinephrine [3, 5]. Adrenal Pheochromocytoma Surrounding Fat Stimulation