Hepatitis E Virus in People Who Use Crack-Cocaine: A Cross-Sectional Study in a Remote Region of Northern Brazil.

作者: Emil Kupek , Aldemir B. Oliveira-Filho , Benedikt Fischer , Luiz Fernando A. Machado , Luísa Caricio Martins

DOI: 10.3390/V13050926

关键词:

摘要: People who use crack-cocaine (PWUCC) have numerous vulnerabilities and pose a challenge to health social assistance services. The exposure pathogens risk situations occur differently according each individual, region group. This study identified the presence, genotypes factors associated with hepatitis E virus (HEV) among community-recruited cohort of 437 PWUCC in northern Brazil. Epidemiological information was collected through community-based assessments interviews. Thereafter, blood fecal samples were tested for HEV using an immunoenzymatic assay, genotype by PCR. Logistic regressions used identify independently HEV. In total, 79 (18.1%) exposed HEV: 73 (16.7%) IgG six + IgM. RNA detected two from IgM IgG. Subtype 3c all samples. low monthly income, unstable housing (e.g., homelessness), ≥40 months, shared equipment. current provides unique initial insights into status remote area Brazil, diverse implications urgently improved diagnosis, prevention, treatment intervention needs.

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