Cytologic diagnosis of acinic-cell carcinoma of salivary glands

摘要: The cytologic findings in fine-needle aspiration (FNA) biopsies obtained from 40 primary and 18 recurrent acinic-cell carcinomas (ACC) were retrospectively analyzed. Cytomorphologically, ACC is characterized by acinar differentiated tumor cells. In addition to these diagnostic clue cells, other types of neoplastic cells including vacuolated resembling oncocytes, nonspecific glandular are encountered. A pronounced lymphocytic reaction a hallmark 10% aspirates. Both the variety cell differentiation observed aspirates may result confusion with salivary gland lesions. differential diagnosis encompasses adenocarcinoma, mucoepidermoid carcinoma, pleomorphic adenoma, Warthin tumor, sebaceous lymphadenoma, benign lymphoepithelial lesion, sialoadenosis, sialadenitis caused radiotherapy, lymphadenitis. Primary ACCs correctly diagnosed 68%; additionally, was suspected or included 15%. Increased familiarity spectrum cytomorphologic potential pitfalls will improve cytodiagnosis this neoplasm. Diagn. Cytopathol. 16:402–412, 1997. © 1997 Wiley-Liss, Inc.