Duration of carriage of carbapenem-resistant Enterobacteriaceae following hospital discharge

摘要: Background Hospitalized carriers of carbapenem-resistant Enterobacteriaceae (CRE) are cohorted under contact precautions, including in the days between rehospitalization and surveillance culture results. This study investigates duration CRE carriage to define populations requiring precautions upon readmission. Methods Patients with CRE-positive during 2009-2010 were followed up by rectal swab cultures taken retrospectively prospectively for or as part clinical follow-up. Results One hundred thirty-seven patients met inclusion criteria, follow-up obtained from 97. Mean time negativity was 387 (95% confidence interval: 312-463). Seventy-eight percent (64/82) had positive at 3 months, 65% (38/58) 6 39% (12/30) 1 year. Duration affected repeat hospitalization ( P  = .001) clinical, opposed surveillance, .002). Conclusion a previous have lower probability readmission if index specimen year passed without further hospitalization. Multiple hospitalizations disease extend carriage. better defines cohorting isolation, thus limiting spread allowing improved allocation infection control measures.