Antimicrobial chloro-hydroxylactones derived from the biotransformation of bicyclic halolactones by cultures of Pleurotus ostreatus

作者: Małgorzata Grabarczyk , Wanda Mączka , Katarzyna Wińska , Barbara Żarowska , Gabriela Maciejewska

DOI: 10.1016/J.BIOORG.2020.104250

关键词:

摘要: Abstract The aim of this research was to test the ability cultures edible fungi biotransform three bicyclic halolactones. substrates (2-chloro-, 2-bromo- and 2-iodo-4,4,6,7-tetramethyl-9-oxabicyclo[4.3.0]nonan-8-one) received by means synthesis were transformed oyster mushroom Pleurotus ostreatus mushrooms genus Armillaria mellea, Marasmius scorodonius Laetiporus sulfureus. converted hydroxyl derivatives only mushroom. Out seven strains - capable hydroxylation all with most effective conversion chlorolactone. Bromo- iodolactone a small extent. Four new chloro-hydroxylactones obtained as biotransformation products. structures products established on basis spectroscopic data. Studies antimicrobial activity performed reference pathogenic microorganisms showed that halolactones caused complete inhibition growth A. alternata F. linii strains. On other hand, able completely inhibit also C. albicans strain.

参考文章(34)
Marco A. Fraatz, Stephanie J.L. Riemer, Regina Stöber, Rüdiger Kaspera, Manfred Nimtz, Ralf G. Berger, Holger Zorn, A novel oxygenase from Pleurotus sapidus transforms valencene to nootkatone Journal of Molecular Catalysis B-enzymatic. ,vol. 61, pp. 202- 207 ,(2009) , 10.1016/J.MOLCATB.2009.07.001
Adi Setyo Purnomo, Toshio Mori, Surya Rosa Putra, Ryuichiro Kondo, Biotransformation of heptachlor and heptachlor epoxide by white-rot fungus Pleurotus ostreatus International Biodeterioration & Biodegradation. ,vol. 82, pp. 40- 44 ,(2013) , 10.1016/J.IBIOD.2013.02.013
Adi Setyo Purnomo, Toshio Mori, Ichiro Kamei, Takafumi Nishii, Ryuichiro Kondo, Application of mushroom waste medium from Pleurotus ostreatus for bioremediation of DDT-contaminated soil International Biodeterioration & Biodegradation. ,vol. 64, pp. 397- 402 ,(2010) , 10.1016/J.IBIOD.2010.04.007
Naama Golan-Rozen, Benny Chefetz, Julius Ben-Ari, Joseph Geva, Yitzhak Hadar, Transformation of the Recalcitrant Pharmaceutical Compound Carbamazepine by Pleurotus ostreatus: Role of Cytochrome P450 Monooxygenase and Manganese Peroxidase Environmental Science & Technology. ,vol. 45, pp. 6800- 6805 ,(2011) , 10.1021/ES200298T
Bronislava Uhnáková, Roland Ludwig, Jana Pěknicová, Ladislav Homolka, Ludmila Lisá, Miroslav Šulc, Alena Petříčková, Fatima Elzeinová, Helena Pelantová, Daniela Monti, Vladimír Křen, Dietmar Haltrich, Ludmila Martínková, Biodegradation of tetrabromobisphenol A by oxidases in basidiomycetous fungi and estrogenic activity of the biotransformation products. Bioresource Technology. ,vol. 102, pp. 9409- 9415 ,(2011) , 10.1016/J.BIORTECH.2011.07.036
Sven Krügener, Ulrich Krings, Holger Zorn, Ralf G. Berger, A dioxygenase of Pleurotus sapidus transforms (+)-valencene regio-specifically to (+)-nootkatone via a stereo-specific allylic hydroperoxidation. Bioresource Technology. ,vol. 101, pp. 457- 462 ,(2010) , 10.1016/J.BIORTECH.2009.08.087
Bruno A Rocha, Marilda D Assis, Ana PF Peti, Luiz AB Moraes, Fernanda L Moreira, Norberto P Lopes, Stanislav Pospíšil, Paul J Gates, Anderson RM de Oliveira, None, In vitro metabolism of monensin A: microbial and human liver microsomes models Xenobiotica. ,vol. 44, pp. 326- 335 ,(2014) , 10.3109/00498254.2013.845707
Małgorzata Grabarczyk, Katarzyna Wińska, Wanda Mączka, Anna Żołnierczyk, Barbara Żarowska, Mirosław Anioł, Lactones with Methylcyclohexane Systems Obtained by Chemical and Microbiological Methods and Their Antimicrobial Activity Molecules. ,vol. 20, pp. 3335- 3353 ,(2015) , 10.3390/MOLECULES20023335
Małgorzata Grabarczyk, Katarzyna Wińska, Wanda Mączka, Barbara Żarowska, Agata Białońska, Mirosław Anioł, Hydroxy lactones with the gem-dimethylcyclohexane system – Synthesis and antimicrobial activity Arabian Journal of Chemistry. ,vol. 12, pp. 2280- 2288 ,(2015) , 10.1016/J.ARABJC.2015.02.018