Orosomucoid (ORM 1) subtyping and formal genetics.
作者： C. Luckenbach , J. K�mpf , H. Ritter
DOI: 10.1007/BF00197162
关键词:
摘要: Orosomucoid (ORM) phenotyping has been performed in 141 families with 407 children from southwest Germany. Eight were observed which duplicated ORM1 genes, F1F2, F1F3, segregated. The family data gave no information about the presence of tandemly F1F4 and F1F5 genes. To date, segregation phenotypes agrees extended formal model: two loci common (*F1, *S) several rare (*F1F2, *F1F3, *F4, *F5) alleles. parental allele frequencies calculated by gene counting as *F1 = 0.5781, *S 0.3901, *F1F2 0.0195, *F4 0.0053, *F1F3 00.0035, *F5 0.0035.
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