DECREASE OF LIVER FUNCTION AFTER TREATMENT OF ANTITUBERCULOSIS DRUGS IN TUBERCULOSIS PATIENTS WITH MALNUTRITION AND ALCOHOL CONSUMPTION Original Article

摘要: Objective: To evaluate the decrease of liver function after treatment antituberculosis drugs-fixed doses combination (ATD-FDC) category 1 in tuberculosis patients with malnutrition and alcohol consumption. Methods: This was an experimental study, a quasi-experimental pretest posttest design, to increase SGPT pulmonary TB malnutrition, treated ATD-FDC for 8 w. Inclusion criteria were: patients, aged ≥ 18 y old, who would receive ATDFDC treatment, did not have level at beginning were willing join study. study conducted all community health centers Kupang, Indonesia. Results: The result this showed that percentage is increased compared before patient without (135.1% vs. 54.7%; p<0.001). difference ≥40 versus<40 15.5 IU/l versus 9.1 (p<0.05). routine consumption habit non-routine 29.3 12.8 (p<0.01). Conclusion: Pulmonary had larger w, those malnutrition. Routine effect on older patients.