Creation of genomic methylation patterns.

摘要: There are two biological properties of genomic methylation patterns that can be regarded as established. First, 5'-CpG-3' dinucleotides within promoters represses transcription, often to undetectable levels. Second, in most cases subject clonal inheritance. These suit for a number roles, although none the current hypotheses proved or disproved. One hypothesis suggests activity parasitic sequence elements is repressed by selective methylation. Features invasive sequences might allow their identification and inactivation discussed terms genome defense hypothesis. Identification cues direct de novo may reveal role (or roles) patterns.