ALAD (δ-aminolevulinic Acid Dehydratase) as Biosensor for Pb Contamination

摘要: Heavy metals are defined as those having a specific density of more than 5 g/cm3. The main threats to human health associated with exposure lead, cadmium, mercury and arsenic (arsenic is metalloid, but usually classified heavy metal) (Jarup 2003). have been used in many different areas for thousands years. Lead has at least 5000 years, early applications including building materials, pigments glazing ceramics, pipes transporting water. In ancient Rome, lead acetate was sweeten old wine, some Romans might consumed much gram day. Mercury allegedly by the salve alleviate teething pain infants, later (from 1300s late 1800s) employed remedy syphilis. Although adverse effects known long time, continues even increasing areas. Since middle 19th century, production increased steeply 100 concomitant emissions environment. Emissions environment occur via wide range processes pathways, air, waters, soil Lead, mercury, cadmium form significant potential threat health, both occupational environmental (Hu 2000). Over past few decades, metal contamination aquatic system attracted attention number researchers all over world. Many industrial agricultural contributed fresh water systems thereby causing on biota (Wang 2002, Dautremepuits 2004). fact that cannot be destroyed through biological degradation ability accumulate make these toxicants deleterious consequently humans who depend products sources food. do mainly tissues animals can public concern beings (Kalay 1999, Ashraf 2005). fact, there several carcinogens, arsenic, chromium nickel. toxic metals, carcinogenicity, modified concurrent other metals. emphasis now testing mixtures chemicals simulate actual conditions. Researches already demonstrated links between polychlorinated biphenyl