Magnetoencephalography based on high-Tc superconductivity: a closer look into the brain?

作者: F. Öisjöen , M. L. Chukharkin , A. Hedström , M. Elam , D. Winkler

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摘要: Magnetoencephalography (MEG) enables the study of brain activity by recording magnetic fields generated neural currents and has become an important technique for neuroscientists in research clinical settings. Unlike liquid-helium cooled low-Tc superconducting quantum interference devices (SQUIDs) that have been at heart modern MEG systems since their invention, high-Tc SQUIDs can operate with liquid nitrogen cooling. The relaxation thermal insulation requirements allows a reduction stand-off distance between sensor room-temperature environment from few centimeters to less than millimeter, where signal strength is significantly higher. Despite this advantage, only used proof-of-principle recordings well-understood evoked activity. Here we show SQUID-based may be capable providing novel information about due close proximity head. We performed single- two-channel SQUID spontaneous two healthy human subjects. demonstrate modulation occipital alpha rhythm mu found motor cortex. Furthermore, discovered uncharacteristically high-amplitude theta-band region brain. Our results suggest provide closer look into

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