Associations between pesticide use and respiratory symptoms: A cross-sectional study in Southern Ghana

摘要: Abstract Background Indiscriminate use of pesticides is a common practice amongst farmers in Low and Middle Income Countries (LMIC) across the globe. However, there little evidence defining whether pesticide associated with respiratory symptoms. Objectives This cross-sectional study was conducted 300 vegetable southern Ghana (Akumadan). Data on collected an interviewed-administered questionnaire. The concentration seven organochlorine 3 pyrethroid assayed urine from sub-population 100 by gas chromatograph equipped electron capture detector (GC-ECD). Results A statistically significant exposure-response relationship years per day spent mixing/applying fumigant wheezing [30–60 days/year: prevalence ratio (PR)=1.80 (95% CI 1.30, 2.50); >60days/year: 3.25 (1.70–6.33), p for trend=0.003] hours [1–2 h/day: 1.20 (1.02–1.41), 3–5 h/day: 1.45 (1.05–1.99), >5 h/day: 1.74 (1.07–2.81), trend=0.0225]; days year fungicide 2.04 (1.31–3.17); 4.16 (1.72–10.08), trend=0.0017] h phlegm production 1.25 (1.05–1.47), 1.55 (1.11–2.17), 1.93 (1.17–3.19), trend=0.0028] 1.10 (1.00–1.50), (1.11–1.72), 1.32 (1.09–2.53), trend=0.0088]; insecticide 1.23 (1.09–1.62), 1.51 (1.20–2.58), 1.85 (1.31–4.15), trend=0.0387] 1.22 (1.02–1.46), 1.49 (1.04–2.12), 1.81 (1.07–3.08), trend=0.0185] were observed. Statistically association also observed combination activities that exposes to all Furthermore, associations insecticides: beta-HCH, heptachlor endosulfan sulfate noted. Conclusions In conclusion, may be at increased risk symptoms as result exposure pesticides.