The Role of Targeted Focal Therapy in the Management of Low-Risk Prostate Cancer: Update on Current Challenges

作者: Daniel W. Smith , Diliana Stoimenova , Khadijah Eid , Al Barqawi

DOI: 10.1155/2012/587139

关键词:

摘要: Prostate cancer is one of the most prevalent cancers among men in United States, second only to nonmelanomatous skin cancer. Since prostate-specific antigen (PSA) testing came into widespread use late 1980s, there has been a sharp increase annual prostate incidence. Cancer-specific mortality, though, relatively low. The majority these will not progress mortal disease, yet who are diagnosed opt for treatment as opposed observation or active surveillance (AS). These thus burdened with morbidities associated aggressive treatments, commonly incontinence and erectile dysfunction, without receiving mortality benefit. It therefore necessary both continue investigating outcomes AS develop less invasive techniques those desire but significant potential quality-of-life side effects seen modalities. goals this paper discuss problems overdiagnosis overtreatment since advent PSA screening well targeted focal therapy (TFT) bridge gap between definitive therapies. Furthermore, patient selection criteria TFT, costs, effects, brachytherapy template-guided three-dimensional mapping biopsies (3DMB) tumor localization also be explored.

参考文章(45)
David F Penson, Active Surveillance: Not Your Father’s Watchful Waiting Oncology. ,vol. 23, ,(2009)
E David Crawford, Al Barqawi, Clare Tempany, Jeffrey K Cohen, Targeted Focal Therapy: A Minimally Invasive Ablation Technique for Early Prostate Cancer Oncology. ,vol. 21, pp. 27- 32 ,(2007)
Nazareno Suardi, Umberto Capitanio, Felix K. H. Chun, Markus Graefen, Paul Perrotte, Thorsten Schlomm, Alexander Haese, Hartwig Huland, Andreas Erbersdobler, Francesco Montorsi, Pierre I. Karakiewicz, Currently used criteria for active surveillance in men with low-risk prostate cancer Cancer. ,vol. 113, pp. 2068- 2072 ,(2008) , 10.1002/CNCR.23827
Al B. Barqawi, Paul D. Maroni, E. David Crawford, Determining Success of Focal Therapy: Biochemical and Biopsy Strategies Wiley‐Blackwell. pp. 143- 152 ,(2011) , 10.1002/9781444346893.CH16
Ian M Thompson, Donna Pauler Ankerst, Chen Chi, M Scott Lucia, Phyllis J Goodman, John J Crowley, Howard L Parnes, Charles A Coltman, Operating Characteristics of Prostate-Specific Antigen in Men With an Initial PSA Level of 3.0 ng/mL or Lower JAMA. ,vol. 294, pp. 66- 70 ,(2005) , 10.1001/JAMA.294.1.66
David G. Bostwick, David J. Waters, Edward R. Farley, Isabelle Meiers, Daniel Rukstalis, William A. Cavanaugh, Haakon Ragde, Martin K. Dineen, Duke Bahn, Stephen Scionti, Richard Babian, David S. Ellis, John C. Rewcastle, Harry B. Burke, Gerald L. Andriole, Gary Onik, Al E. Barqawi, John Maksem, Winston E. Barzell, Group consensus reports from the Consensus Conference on Focal Treatment of Prostatic Carcinoma, Celebration, Florida, February 24, 2006. Urology. ,vol. 70, pp. 42- 44 ,(2007) , 10.1016/J.UROLOGY.2007.07.037
Takeo Nomura, Hiromitsu Mimata, Focal therapy in the management of prostate cancer: an emerging approach for localized prostate cancer. Advances in Urology. ,vol. 2012, pp. 391437- 391437 ,(2012) , 10.1155/2012/391437
Kathryn F. Sullivan, E. David Crawford, Targeted focal therapy for prostate cancer: a review of the literature. Therapeutic Advances in Urology. ,vol. 1, pp. 149- 159 ,(2009) , 10.1177/1756287209338708
Holly Sullivan, M. Scott Lucia, Priya N. Werahera, E. David Crawford, Shandra S. Wilson, Kathleen C. Torkko, Daisaku Hirano, J. Scott Stewart, Craig Brammell, R. Storey Wilson, Nozomu Kawata, Clinical staging of prostate cancer: a computer‐simulated study of transperineal prostate biopsy BJUI. ,vol. 96, pp. 999- 1004 ,(2005) , 10.1111/J.1464-410X.2005.05801.X
Vincenzo Scattoni, Alexandre Zlotta, Rodolfo Montironi, Claude Schulman, Patrizio Rigatti, Francesco Montorsi, Extended and Saturation Prostatic Biopsy in the Diagnosis and Characterisation of Prostate Cancer: A Critical Analysis of the Literature European Urology. ,vol. 52, pp. 1309- 1322 ,(2007) , 10.1016/J.EURURO.2007.08.006