摘要: The recognition of anions using abiotic hosts is an area interest in the field molecular recognition, which recently has been rapidly expanding. variety shapes and sizes anionic targets resulted rather elaborate receptor designs that have made it possible to investigate propert ies anion recognition. These efforts are directed towards modeling molecular-recognition characteristics enzymes focused on industrial applications such as sensing separation. Within this context, paper focuses research done within Anslyn group at physical studies systems use these data other fields. ability design study synthetic abiot ic receptors for aqueous organ media furthers our understanding several phenomena. For example, or encapsulation serves advance binding forces involved interactions between guest host.' Ion-pairing behavior, hydrogen bonding, geometric considerations, interplay microenvironment with pK. values, lowering activation barriers reactions areas particular interest.' Also pertinent development techniques signal events spectroscopically.' Specifically, group, knowledge garnered applied waste-water analysis, blood artificial , food beverage quality control, RNA hydrolysis. Advances well documented through review articles.' structural considerations used anion-complexing agent size, charge, shape . Inorganic ions, organic anions, large biological common targets. architectures can be described polyfunctionalized macrocycles," clefts," tweezers," bowls," metallic sites.