作者: J. Glover
DOI: 10.1016/S0083-6729(08)60869-9
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摘要: Publisher Summary The relationship between the vitamin A activity of yellow carotenes plants and colorless growth factor in liver oils became clearer after Moore demonstrated that carotene was metabolized animal body to form A, which stored liver. resemblance structure elucidated by Karrer others., half 8-carotene molecule suggested them it might be formed from latter central fission involving addition equivalent two molecules water. enzyme carotenase concerned then sought tissue where appears highest concentration. experimental evidence at time for its presence yielded conflicting results, general case regarded as not proved. Although everyone agreed β-carotene administered orally transformed into A; great difficulty encountered demonstrating conversion when provitamin parenterally.