In vivo EPR tooth dosimetry for triage after a radiation event involving large populations.

摘要: The management of radiation injuries following a catastrophic event where large numbers people may have been exposed to life-threatening doses ionizing will rely critically on the availability and use suitable biodosimetry methods. In vivo electron paramagnetic resonance (EPR) tooth dosimetry has number valuable unique characteristics capabilities that help enable effective triage. We produced prototype deployable EPR dosimeter tested it in several vitro studies characterize performance utility at state art. This report focuses recent advances technology, which strengthen evidence can provide practical, accurate, rapid measurements context its intended triage victims an improvised nuclear device. These signal is stable, accurate within 0.5 Gy, be successfully carried out vivo. stability over time radiation-induced from whole teeth was measured confirm long-term better behavior hours irradiation. Dosimetry were taken for five pairs natural human upper central incisors mounted simple anatomic mouth model demonstrates ability achieve Gy standard error inverse dose prediction. An assessment intact estimation screening performed with volunteer subjects who not significant levels patients undergone total body irradiation as part bone marrow transplant procedures. Based these previous evaluations system, concluded this system could very resource aid massive radiological event.