Chapter 6 - Optophysiological Approaches to Learning and Memory in Drosophila melanogaster

摘要: Localizing and determining biochemical physiological mechanisms in the brain that are causally related to experience-dependent changes of behavior (i.e., learning) can be accomplished by combining different experimental approaches. First, disabling neuronal structure function, such as mutations leading ablation neurons or reversibly blocking synaptic transmission, provide information about which structures processes required for learning. Second, monitoring activity during after learning informs processing correlate with learning, memory formation, retrieval. Third, artificial induction used mimic learning-induced function. Advances development molecular tools optically monitor correlates manipulate through light temperature increase have substantially expanded toolkit In this chapter, we review applications these techniques analyzing underlying associative olfactory Drosophila melanogaster .