Sensitivity of estimated muscle force in forward simulation of normal walking.

摘要: Generic muscle parameters are often used in muscle-driven simulations of human movement to estimate individual forces and function. The results may not be valid since properties vary from subject subject. This study investigated the effect using generic a forward simulation on force estimation. We generated normal walking OpenSim examined sensitivity perturbations parameters, including number muscles, maximum isometric force, optimal fiber length, tendon slack length. found that when changing muscles included model, only magnitude estimated was affected. Our also suggest it is especially important use accurate values length for ankle plantar flexors knee extensors. Changes production by one were typically compensated changes same functional group, or antagonistic group. Conclusions regarding function based with musculoskeletal should interpreted caution.