Pregnancy and perinatal outcomes in migraineurs using sumatriptan: a prospective study

摘要: Background: Sumatriptan is an acute treatment for migraine which often used by women in their child-bearing years, and who become unexpectedly pregnant. Within the context of post-marketing use sumatriptan injection migraine, compliance with approved labeling, we wished to compare perinatal pregnancy outcomes did not drug after conception. Methods: Open-label, prospective study conducted 12,339 migraineurs (including 9,861 women) whose demography consumption pattern injections were typical, predicted include 150 pregnancies. Outcome was end-point. Results: There 168 173 pregnancies that well-documented. only prior conception 92 cases. 76 first trimester exposures sumatriptan. no differences outcome between two groups. Conclusions: Perinatal differ patients had conception, at resolution these sample sizes. This design complements ongoing registry, now widened exposed all formulations