Combination of Antimicrobial Starters for Feed Fermentation: Influence on Piglet Feces Microbiota and Health and Growth Performance, Including Mycotoxin Biotransformation in vivo.

摘要: The aim of this study was to apply a combination the microbial starters Lactobacillus uvarum LUHS245, casei LUHS210, Pediococcus acidilactici LUHS29, and pentosaceus LUHS183 for feed fermentation evaluate influence on acidity microbiological characteristics, as well piglet feces microbiota, health, growth performance. Additionally, mycotoxin biotransformation analyzed, including masked mycotoxins, in samples. 36-day experiment conducted using 25-day-old Large White/Norwegian Landrace (LW/NL) piglets with an initial body weight 6.9-7.0 kg, which were randomly distributed into two groups (in each 100 piglets): control group, fed basal diet (based barley, wheat, potato protein, soybean protein concentrate, whey powder), treated fermented at 500 g kg-1 total feed. Compared commercially available lactic acid bacteria (LAB) combination, novel LAB mixture effectively reduced pH (on average 3.65), produced 2-fold higher content L(+) acid, increased viable count [on 8.8 log10 colony-forming units (CFU) g-1], led stable during entire test period (36 days). Fecal microbiota analysis showed number probiotic particularly Lactobacillus, when compared group end experiment. This finding indicates that can modify profile change gut pigs. In piglets' blood (at day 61), serum high-density lipoprotein (HDL) cholesterol triglycerides (TG) significantly higher, but levels T4, glucose, K, alkaline phosphatase (AP), urea decreased (p ≤ 0.05) group. Mycotoxin alternariol monomethyl ether (AME) altenuene found 61-day-old However, AME not feces. Feed is promising means modulate essential improve nutrient absorption, performance, health parameters. new composition suggests dietary strategy positively manipulate chemicals bio-safety ecology reduce antimicrobials use pig production increase local stock uses economical effectiveness process.