Graphical and numerical representations of DNA sequences: statistical aspects of similarity.

摘要: New approaches aiming at a detailed similarity/dissimilarity analysis of DNA sequences are formulated. Several corrections that enrich the information which may be derived from alignment methods proposed. The take into account distributions along aligned bases (neglected in standard methods). As consequence, different aspects similarity, as for example asymmetry gene structure, studied either using new similarity measures associated with four-component spectral representation or introduced this paper. to and statistical distribution moment-based descriptors applied studies β-globin across species. supplemented by histones H1 H4 coding sequences. data described according latest version EMBL database. work is concise review state-of-art graphical representations