Positive staining for cellulose in oral pulse granuloma

作者: Sirke Virkkunen , Henrik Wolff , Caj Haglund , Casper Højgaard , Jakob Rahr Winther

DOI: 10.1016/J.OOOO.2016.11.022

关键词:

摘要: Objective Oral pulse granuloma (OPG) is an oral inflammatory lesion characterized by the presence of hyaline rings with numerous multinucleated giant cells. The etiopathogenesis this thus far unclear, as composition rings. Our aim was to investigate whether contain cellulose. Study Design Using a newly developed staining method for cellulose, we studied 18 histologic samples diagnosed OPG, in addition 3 originally “normal” foreign body reactions. In our study, visualization cellulose based on its specific binding carbohydrate module β-1,4-glycanase. Results All OPG were positive localized addition, 1 (of 3), first reaction without rings, horseradish peroxidase staining. Conclusions We show time that present lesions, indicating might be initial cause formation these lesions.

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