作者: Tammy J Bungard , Bruce Ritchie , Jennifer Bolt , William M Semchuk
DOI: 10.1136/BMJOPEN-2018-022064
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摘要: Objective To report the proportion of patients discharged directly from emergency department (ED) on traditional therapy (parenteral anticoagulant±warfarin) or a direct oral anticoagulant (DOAC) for management acute venous thromboembolism (VTE). Design Retrospective medical record review across four EDs in Edmonton, Alberta, two Regina, Saskatchewan and three rural Alberta. Setting April 2014 through March 2015. Participants Discharged ED with VTE. Patients were excluded if they had another indication anticoagulants, pregnant/breastfeeding anticipated lifespan Primary secondary outcome measures Primarily, that prescribed DOAC, comparisons between Regina Secondarily, selection was compared based deep vein thrombosis (DVT) versus pulmonary embolism (PE) clot burden. Dosing DOACs assessed (when applicable) follow-up community compared. Results After screening 1723 patients, 417 (24.2%) included DVT PE occurring 65.5% 34.5%, respectively. More Edmonton (43%) than (7%). Overall, majority (70.7%), 27.8% receiving DOAC. Uptake DOAC use highest Alberta (53.3%) (29.6%) (12.1%). more commonly (34.0%) (24.5%) (p=0.04), proximal distal (28.4% 17.3%; p Conclusions Regional variation discharging is evident. While most common, uptake modest given timing approval.