Semaphorins: mediators of repulsive growth cone guidance
作者： Alex L. Kolodkin
DOI: 10.1016/0962-8924(96)81033-6
关键词:
摘要: During development, neuronal growth cones encounter a variety of guidance cues while mediating axon path finding, target recognition and synapse formation. It is clear that repulsive mechanisms play an essential role in these processes. The semaphorin gene family, which conserved from invertebrates to mammals, includes members mediate guidance. Molecular cellular analysis this family providing insight into how inhibitory function during neurodevelopment.
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