The International Agency for Research on Cancer (IARC) evaluation of the carcinogenicity of outdoor air pollution: focus on China
作者： Dana Loomis , Wei Huang , Guosheng Chen
关键词:
摘要: The International Agency for Research on Cancer (IARC) has classified outdoor air pollution and the particulate matter (PM) in as carcinogenic to humans, based sufficient evidence of carcinogenicity humans experimental animals strong support by mechanistic studies. data with important contributions evaluation are reviewed, highlighting particular relevance China, implications respect China discussed. levels Chinese cities among highest observed world today frequently exceed health-based national international guidelines. Data from high-quality epidemiologic studies Asia, Europe, North America consistently show positive associations between lung cancer PM exposure other indicators pollution, which persist after adjustment risk factors, such tobacco smoking. Epidemiologic limited but nevertheless indicate an increased associated several pollutants. Excess is also exposed polluted or extracted PM. species markers genetic damage that have been linked humans. Numerous especially biomarker populations, genotoxic IARC indicates both need further research into risks urgent act reduce population.
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