Usefulness of white blood cell differential for early diagnosis of surgical wound infection following spinal instrumentation surgery.

摘要: STUDY DESIGN The white blood cell (WBC) count and WBC differential were measured prospectively in patients after spinal instrumentation surgery with or without surgical wound infection. OBJECTIVES.: To investigate the usefulness of for early diagnosis infection surgery. SUMMARY OF BACKGROUND DATA Renewed elevation C-reactive protein (CRP) WBC, gallium scan, CRP/transthyretin mass concentration ratio reported METHODS A total 39 enrolled this study: 13 who developed within 2 weeks (infection group) 26 comparable those included group regard to age, sex, techniques used (control group). determined before RESULTS In both groups, percentage number neutrophils showed nearly same change until postoperative 4 days (day 4). However, group, these parameters had increased day 4. lymphocytes decreased 10% less 1,000/microL on 1, respectively. These lymphocyte began gradually normalize returned preoperative level 3 control group. On other hand, remained 1,000/muL 11 infection, significantly as CONCLUSION Lymphopenia represents immunodepression status, thus indicating susceptibility which may lead development If lymphopenia is diagnosed possible, can be treated promptly removing instruments.