摘要: Background. The DSM concept of ‘major depression’ has accrued increased status but demonstrated limited utility since inception.Method. An historical overview models depression and the initially perceived advantages presented by are before detailing its limitations in application.Results. Challenges to provided examining conceptual model, validity, information generated aetiological treatment efficacy studies.Conclusion. It is argued that led sterility research clinical practice, there a need for paradigm shift modelling classifying depressive disorders.
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