Molecular biomarkers of lung carcinoma.

摘要: Lung carcinoma is still the leading cause of cancer deaths in men and women. There a constantly increasing need to find molecular biomarkers for lung which can be used risk stratification, early detection, treatment selection, prognosis monitoring recurrence. Recent advances imaging improved bronchoscopic techniques have intensified interest screening techniques, especially new markers help cytopathologists make definitive diagnosis on very small specimens non-invasive, non-expensive, simple efficient manner. Several decades intensive research originated numerous potential but only few turned out useful clinic. The review describes types biomarkers, sources their identification therapy. A deep understanding each biomarker will key efficiently diagnose carcinomas direct patients toward beneficial drugs based individual patient profile.