Novel biomarkers for early diagnosis of acute kidney injury.

作者: Sean M Bagshaw

DOI: 10.1517/17530059.2.9.1041

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摘要: Background: Acute kidney injury (AKI) is a common and serious problem in critically ill patients. Tests currently used to detect AKI (i.e., serum creatinine, urea various urinary indices) often result delays detection of clinically relevant injury. This delayed translates into potential missed opportunity for therapeutic interventions at time when damage may be limitable or reversible. also recognized as reason the poor clinical outcomes associated with AKI. Objectives: To appraise recent literature characterizing several novel biomarkers, including neutrophil gelatinase-associated lipocalin, IL-18 molecule-1, which are capable detecting an earlier phase Also discuss pitfalls current conventional testing Method: Narrative review. Conclusions: These biomarkers can still reversible, allow earl...

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