Streptococcus suis: an emerging human threat.

摘要: In the world of Streptococcus, S. suis has been somewhat neglected. Indeed, at this year’s Lancefield International Symposium on Streptococci and Streptococcal Diseases, only one oral presentation was devoted to pathogen. However, perception should change, because is emerging as an important threat human health. encapsulated Grampositive coccus possessing cell-wall antigens related group D. There are 35 serotypes that have described basis composition polysaccharide capsule [1]. infections considered be a major problem worldwide in swine industry. The pathogen’s natural habitat upper respiratory tract pigs, well genital alimentary tracts pig carrier rate near 100%, and, absence treatment, mortality reaches 20% [2]. most clinical feature associated with infection pigs meningitis. severe cases, found dead no premonitory signs. Other manifestations arthritis, endocarditis, pneumonia, rhinitis, abortion, vaginitis Until recently, disease humans rare [3, 4]. Since first case Denmark 1968 [5] before 2005, 250 were reported Europe Asia. recently identified third common cause communityacquired bacterial meningitis Hong Kong, behind pneumoniae Mycobacterium tuberculosis [6], leading adult Vietnam [7]. Mysteriously, 2 cases Canada [8, 9], 1, very United States [10]. Although epidemiology remains largely undefined, nearly all can ascribed either handling or consumption unprocessed pork meat close contact pigs. Therefore, infected people farmers, abattoir workers, inspectors, butchers, veterinarian practitioners [4]. humans, usually produces purulent nonpurulent Additionally, cellulitis, peritonitis, rhabdomyolysis, spondylodiscitis, uveitis, endopthalmitis may occur [4, 11, 12]. Both shock high also [13, 14]. One striking suis–related complication deafness and/or vestibular dysfunction, which occurs consistently higher than for other meningitis-causing bacteria 50% 65% Asia, respectively [11, Most attributed serotype strains; however, due 4, 14, 16 Strains isolated from phenotypically genotypically similar those recovered within same geographical region [15].