Clinical significance of right ventricular dysfunction in left ventricular non-compaction cardiomyopathy

摘要: Left ventricular non-compaction (LVNC) is described as the persistence of trabeculated myocardium in left ventricle (LV) and optimally assessed by cardiac magnetic resonance (CMR). Right (RV) involvement LVNC remains poorly studied. Consecutive patients (N = 14) diagnosed with CMR were Their clinical data analyzed. In addition, assessment included quantification LV RV volumes, mass, ejection fraction (EF), wall motion score, non-compacted segments to compacted ratios. Average age presentation was 33.1 ± 17.6 years old, 9 males (64%). Of these patients, 7 (50%) presented acute heart failure 3 (21%) syncope, including 1 documented tachycardia. EF < 35% identified patients. Patients at a higher median New York Heart Association class (1 [IQR 1–2] vs. 2–4], P 0.021) had significantly lower (50.7% 15.4 21.8% 19.9, 0.029), end diastolic (100.9 ml/m2 22.3 159.1 36.0, 0.002) systolic volume indices (52.0 25.8 129.1 48.4, 0.002), score index (1.3 0.5 2.2 0.6, 0.004) ratio (3.3 0.6 4.1 0.8, 0.026). All 4 that tachycardia also dysfunction. dysfunction present half LVNC. Significant seems be marker advanced may carry worse prognosis. Further studies larger sample are needed confirm those observations.