Bench-to-bedside translation of magnetic nanoparticles.

作者: Dhirender Singh , JoEllyn M McMillan , Alexander V Kabanov , Marina Sokolsky-Papkov , Howard E Gendelman

DOI: 10.2217/NNM.14.5

关键词:

摘要: Magnetic nanoparticles (MNPs) are a new and promising addition to the spectrum of biomedicines. Their promise revolves around broad versatility biocompatibility MNPs their unique physicochemical properties. Guided by applied external magnetic fields, represent cutting-edge tool designed improve diagnosis therapy range inflammatory, infectious, genetic degenerative diseases. hyperthermia, targeted drug gene delivery, cell tracking, protein bioseparation tissue engineering but few applications being developed for MNPs. toxicities linked shape, size surface chemistry real must be addressed before clinical use is realized. This article presents both perils this nanotechnology, with an eye towards opportunity in translational medical science.

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