Combined Malnutrition and Frailty Significantly Increases Complications and Mortality in Patients Undergoing Elective Total Hip Arthroplasty.

摘要: BACKGROUND The demand for total hip arthroplasty (THA) continues to rise. While prior work has examined frailty and malnutrition independently, the additive effects of these conditions are unknown. Therefore, purpose this study was evaluate individual combined influence in elective THA patient. METHODS This is a retrospective cohort study. Patients undergoing elective, primary were identified from American College Surgeons-National Surgery Quality Improvement Program database. with fracture excluded. Preoperative serum albumin levels (malnutrition = <3.5 g/dL) 5-item modified index scores (≥2 = frail) collected. Four cohorts created: (1) Healthy (N), (2) Frail-only (F), (3) Hypoalbuminemia-only (H), (4) Hypoalbuminemia frail (HF). Demographic complication data collected, statistical analysis performed comparing complications between cohorts. RESULTS 105,997 patients inclusion. majority (82%) healthy (14% F, 3% H, 1% HF). HF group found have higher odds compared all other groups (HF vs N; ratio [OR] 3.7, 95% confidence interval [CI] 3.07-4.46, P < .001). Notably, had 1.9% 30-day mortality rate OR 12.66, CI 7.81-20.83, Additionally, increased resource utilization when (P CONCLUSIONS Frailty both represent physiologically compromised states but only weakly correlated. concurrent presence patient significant detrimental impacts. Further research will be needed delineate what degree risk factors modifiable.