Epilepsy as a dynamic disease of neuronal networks
作者： Fernando H. Lopes Da Silva , Jan A. Gorter , Wytse J. Wadman
DOI: 10.1016/B978-0-444-52898-8.00003-3
关键词:
摘要: Epilepsy is a dynamic disease of neuronal networks. To understand how epileptic seizures occur, it necessary to take into account that the brain subjects able function in two very distinct modes: normal state and characterized by abnormal oscillations, i.e., seizures. A main question transition (i.e., bifurcation) from can place. Such transitions do not occur easily due set parameters maintains stability In subjects, however, these are disturbed so threshold for much lower may spontaneously. This essential difference between dynamics an brain. Here we consider, first, aspects networks be maintained epilepsy. Thereafter discuss behavior important systems with respect epilepsy: thalamocortical hippocampal systems. Finally, involved identified clinic analyzed.
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P Gloor, A Pellegrini, G.K Kostopoulos, Effects of changes in cortical excitability upon the epileptic bursts in generalized penicillin epilepsy of the cat. Electroencephalography and Clinical Neurophysiology. ,vol. 46, pp. 274- 289 ,(1979) , 10.1016/0013-4694(79)90202-5
X. J. Wang, D. Golomb, J. Rinzel, Emergent spindle oscillations and intermittent burst firing in a thalamic model: specific neuronal mechanisms. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 92, pp. 5577- 5581 ,(1995) , 10.1073/PNAS.92.12.5577
Fernando Lopes da Silva, Wouter Blanes, Stiliyan N. Kalitzin, Jaime Parra, Piotr Suffczynski, Demetrios N. Velis, Epilepsies as Dynamical Diseases of Brain Systems : Basic Models of the Transition Between Normal and Epileptic Activity Epilepsia. ,vol. 44, pp. 72- 83 ,(2003) , 10.1111/J.0013-9580.2003.12005.X
P. Suffczynski, S. Kalitzin, F.H. Lopes Da Silva, Dynamics of non-convulsive epileptic phenomena modeled by a bistable neuronal network. Neuroscience. ,vol. 126, pp. 467- 484 ,(2004) , 10.1016/J.NEUROSCIENCE.2004.03.014
Z. Liu, M. Vergnes, A. Depaulis, C. Marescaux, Involvement of intrathalamic GABAB neurotransmission in the control of absence seizures in the rat. Neuroscience. ,vol. 48, pp. 87- 93 ,(1992) , 10.1016/0306-4522(92)90340-8
M. A. Gainey, J. R. Hurvitz-Wolff, M. E. Lambo, G. G. Turrigiano, Synaptic Scaling Requires the GluR2 Subunit of the AMPA Receptor The Journal of Neuroscience. ,vol. 29, pp. 6479- 6489 ,(2009) , 10.1523/JNEUROSCI.3753-08.2009
Marco de Curtis, Denis Paré, Rodolfo R. Lliás, The electrophysiology of the olfactory-hippocampal circuit in the isolated and perfused adult mammalian brain in vitro. Hippocampus. ,vol. 1, pp. 341- 354 ,(1991) , 10.1002/HIPO.450010402
S.C. Ponten, F. Bartolomei, C.J. Stam, Small-world networks and epilepsy: graph theoretical analysis of intracerebrally recorded mesial temporal lobe seizures. Clinical Neurophysiology. ,vol. 118, pp. 918- 927 ,(2007) , 10.1016/J.CLINPH.2006.12.002
Hugh R. Wilson, Jack D. Cowan, Excitatory and Inhibitory Interactions in Localized Populations of Model Neurons Biophysical Journal. ,vol. 12, pp. 1- 24 ,(1972) , 10.1016/S0006-3495(72)86068-5
Joseph Glykys, Istvan Mody, Hippocampal Network Hyperactivity After Selective Reduction of Tonic Inhibition in GABAA Receptor α5 Subunit–Deficient Mice Journal of Neurophysiology. ,vol. 95, pp. 2796- 2807 ,(2006) , 10.1152/JN.01122.2005