Redistribution of blood flow by prostaglandin F2α in the rabbit ovary

作者: Miles J. Novy , Michael J. Cook

DOI: 10.1016/0002-9378(73)90042-2

关键词:

摘要: Abstract Radioactive microspheres were used to measure ovarian and regional blood flow in unanesthetized estrous pseudopregnant rabbits. Ovarian was 5 times higher on Day 9 of pseudopregnancy (9.4 ml. per gram minute) than before ovulation (1.7 minute). The corpora lutea received more 80 cent the total accounted for postovulatory hyperemia. Intravenous injection prostaglandin F 2α (PGF ) caused a significant redistribution flow; corpus luteum decreased while interstitial follicular tissue increased. Our results suggest that prostaglandins play role regulating microcirulation PGF constricts afferent vessels or small arteriovenous anastomoses.

参考文章(15)
Martin H. Lees, John D. Hill, A.John Ochsner, Carole L. Thomas, Miles J. Novy, Maternal placental and myometrial blood flow of the rhesus monkey during uterine contractions American Journal of Obstetrics and Gynecology. ,vol. 110, pp. 68- 81 ,(1971) , 10.1016/0002-9378(71)90219-5
E W Horton, Hypotheses on physiological roles of prostaglandins. Physiological Reviews. ,vol. 49, pp. 122- 161 ,(1969) , 10.1152/PHYSREV.1969.49.1.122
F. R. BLATCHLEY, B. T. DONOVAN, Luteolytic effect of prostaglandin in the guinea-pig. Nature. ,vol. 221, pp. 1065- 1066 ,(1969) , 10.1038/2211065A0
J. A. McCRACKEN, A. UNO, J. R. GODING, Y. ICHIKAWA, D. T. BAIRD, The in-vivo effects of sheep pituitary gonadotrophins on the secretion of steroids by the autotransplanted ovary of the ewe. Journal of Endocrinology. ,vol. 45, pp. 425- 440 ,(1969) , 10.1677/JOE.0.0450425
M. De Burgh Daly, C. J. Lambertsen, A. Schweitzer, Observations on the volume of blood flow and oxygen utilization of the carotid body in the cat The Journal of Physiology. ,vol. 125, pp. 67- 89 ,(1954) , 10.1113/JPHYSIOL.1954.SP005143
J. A. McCRACKEN, J. C. CARLSON, M. E. GLEW, J. R. GODING, D. T. BAIRD, K. GREEN, B. SAMUELSSON, Prostaglandin F 2 identified as a luteolytic hormone in sheep. Nature. ,vol. 238, pp. 129- 134 ,(1972) , 10.1038/NEWBIO238129A0
HAROLD G. SPIES, JESSAMINE HILLIARD, CHARLES H. SAWYER, Maintenance of corpora lutea and pregnancy in hypophysectomized rabbits. Endocrinology. ,vol. 83, pp. 354- 367 ,(1968) , 10.1210/ENDO-83-2-354
J. A. McCRACKEN, M. E. GLEW, R. J. SCARAMUZZP, Corpus Luteum Regression Induced by Prostaglandin F2α1 The Journal of Clinical Endocrinology and Metabolism. ,vol. 30, pp. 544- 546 ,(1970) , 10.1210/JCEM-30-4-544
W. E. Huckabee, C. Crenshaw, L. B. Curet, L. Mann, D. H. Barron, THE EFFECT OF EXOGENOUS OESTROGEN ON THE BLOOD FLOW AND OXYGEN CONSUMPTION OF THE UTERUS OF THE NON-PREGNANT EWE Quarterly Journal of Experimental Physiology and Cognate Medical Sciences. ,vol. 55, pp. 16- 24 ,(1970) , 10.1113/EXPPHYSIOL.1970.SP002046
P. L. KEYES, A. V. NALBANDOV, Maintenance and Function of Corpora Lutea in Rabbits Depend on Estrogen Endocrinology. ,vol. 80, pp. 938- 946 ,(1967) , 10.1210/ENDO-80-5-938