Synthesis of Doxorubicin loaded magnetic chitosan nanoparticles for pH responsive targeted drug delivery.

作者: Gozde Unsoy , Rouhollah Khodadust , Serap Yalcin , Pelin Mutlu , Ufuk Gunduz

DOI: 10.1016/J.EJPS.2014.05.021

关键词:

摘要: … CS MNPs have pH responsive release characteristics. The cellular internalization of Doxorubicin loaded CS … present in the FTIR spectrum of Doxorubicin loaded CS MNPs as shifted to …

参考文章(40)
Doğa Kavaz, Sedat Odabaş, Eylem Güven, Murat Demirbilek, Emir Baki Denkbaş, Bleomycin Loaded Magnetic Chitosan Nanoparticles as Multifunctional Nanocarriers Journal of Bioactive and Compatible Polymers. ,vol. 25, pp. 305- 318 ,(2010) , 10.1177/0883911509360735
J. Berger, M. Reist, J.M. Mayer, O. Felt, N.A. Peppas, R. Gurny, Structure and interactions in covalently and ionically crosslinked chitosan hydrogels for biomedical applications European Journal of Pharmaceutics and Biopharmaceutics. ,vol. 57, pp. 19- 34 ,(2004) , 10.1016/S0939-6411(03)00161-9
Chiara Riganti, Claudia Voena, Joanna Kopecka, Paola Antonia Corsetto, Gigliola Montorfano, Emanuele Enrico, Costanzo Costamagna, Angela Maria Rizzo, Dario Ghigo, Amalia Bosia, Liposome-encapsulated doxorubicin reverses drug resistance by inhibiting P-glycoprotein in human cancer cells. Molecular Pharmaceutics. ,vol. 8, pp. 683- 700 ,(2011) , 10.1021/MP2001389
Susana Rodrigues, Marita Dionísio, Carmen Remuñán López, Ana Grenha, Biocompatibility of Chitosan Carriers with Application in Drug Delivery Journal of Functional Biomaterials. ,vol. 3, pp. 615- 641 ,(2012) , 10.3390/JFB3030615
Mei Lin Tan, Peter F.M. Choong, Crispin R. Dass, Review: doxorubicin delivery systems based on chitosan for cancer therapy Journal of Pharmacy and Pharmacology. ,vol. 61, pp. 131- 142 ,(2009) , 10.1211/JPP.61.02.0001
Ji Sun Park, Tae Hee Han, Kuen Yong Lee, Sung Soo Han, Jung Jin Hwang, Dae Hyuk Moon, Sang Yoon Kim, Yong Woo Cho, N-acetyl histidine-conjugated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: endocytosis, exocytosis and drug release. Journal of Controlled Release. ,vol. 115, pp. 37- 45 ,(2006) , 10.1016/J.JCONREL.2006.07.011
Ana Grenha, Chitosan nanoparticles: a survey of preparation methods Journal of Drug Targeting. ,vol. 20, pp. 291- 300 ,(2012) , 10.3109/1061186X.2011.654121
Agatha SE Ojugo, Paul MJ McSheehy, Dominick JO McIntyre, Cheryl McCoy, Marion Stubbs, Martin O Leach, Ian R Judson, John R Griffiths, None, Measurement of the extracellular pH of solid tumours in mice by magnetic resonance spectroscopy: a comparison of exogenous 19F and 31P probes NMR in Biomedicine. ,vol. 12, pp. 495- 504 ,(1999) , 10.1002/(SICI)1099-1492(199912)12:8<495::AID-NBM594>3.0.CO;2-K
Zonghua Liu, Yanpeng Jiao, Yifei Wang, Changren Zhou, Ziyong Zhang, Polysaccharides-based nanoparticles as drug delivery systems Advanced Drug Delivery Reviews. ,vol. 60, pp. 1650- 1662 ,(2008) , 10.1016/J.ADDR.2008.09.001