Supplemental Bacillus subtilis DSM 32315 manipulates intestinal structure and microbial composition in broiler chickens.

摘要: Knowledge about the modulation of gut microbiota improves our understanding underlying mechanism by which probiotic treatment benefits chickens. This study examined effects Bacillus subtilis DSM 32315 on intestinal structure and microbial composition in broilers. Broiler chicks were fed basal diets without or with B. supplementation (1.0 × 109 spores/kg diet). Supplemental increased average body weight daily gain, as well elevated villus height to crypt depth ratio ileum Multi-dimension analysis showed a certain degree separation between cecal from control groups. Increased Firmicutes abundance reduced Bacteroidetes cecum observed responded addition, also abundances Christensenellaceae Caulobacteraceae, simultaneously decreased potentially harmful bacteria such Vampirovibrio, Escherichia/Shigella Parabacteroides. Network signified that addition improved interaction pattern within broilers, however, it exerted little influence metabolic pathways comparison functional prediction metagenomes. In conclusion, supplemental growth performance could be at least partially responsible manipulation composition.