CONCENTRATIONS OF 6-OXO-PROSTAGLANDIN F1α IN THE MATERNAL AND FOETAL PLASMA OF SHEEP DURING SPONTANEOUS AND INDUCED PARTURITION

摘要: The concentrations of 6-oxo-prostaglandin F(1α) (6-oxo-PGF(1α) have been determined in maternal and foetal plasma from none chronically catheterized sheep during late pregnancy parturition. Labour occurred either spontaneously (three sheep) or was induced by continuous intrafoetal infusion Synacthen (ACTH 1-24; 0.24 mg/24 hr three dexamethasone (1 hr; sheep). During spontaneous Synacthen-induced parturition, 6-oxo-PGF(1α) remained at basal levels until 24 before delivery. At varying times the delivery, were generally increased. When parturition with dexamethasone, however, no increase observed although concentration raised close to